St John’s wort – Hypericum perforatum

August 20, 2020/0 Comments/in Home Remedies /by Dr. Todd Stone

St John’s wort: Scientific Evidence

depression Randomized Clinical Trials (RCTs) are considered the highest form of scientific evidence. A group of people with the same condition are divided into two groups, and randomly assigned to receive the medicine or a placebo. Neither the patient nor the doctors know which group they are in until the results are assessed.

The following are RCTs in the National Library of Medicine listed when you search “St Johns Wort Randomized Clinical Trial.”

Complement Ther Med Aug 2019. Conclusion: Treatment with Hypericum perforatum is an efficient way of reducing hot flashes, menopausal symptoms, and depression in postmenopausal women. (1)

Climacteric Aug 2019. In conclusion, with its positive benefit-risk profile, Black Cohosh and St Johns Wort may offer a safe non-hormonal therapeutic option for breast cancer survivors receiving endocrine therapy. (2)

J Psychopharmacol Feb 2019. Results: St John’s wort treatment produced similar changes to other antidepressants, without side effects, for example reducing recognition of disgusted faces and attention to fearful faces, while increasing memory for positive words. (3)

Psychopharmacol (Berl) Feb 2019. Conclusions: The results indicate that acute treatment with small (250 mg) dosages of H. perforatum has a positive effect on the capacity of short-term verbal memory. (4)

Psychopharmacol (Berl) Jan 2018. Conclusions: Our findings suggest that a single oral dose of HYP extract modulates cortical plasticity in healthy subjects and provide new insight into its possible mechanism of action in humans. (5)

Phytotherapy Res Sep 2017. Results: At 3 months, women in the herbal group recorded a reduction in oligomenorrhoea (missing menstruation) of 32.9% compared with controls, estimated as a large effect. Other significant improvements were found for body mass index; insulin and luteinizing hormone; blood pressure; quality of life; depression, anxiety and stress; and pregnancy rates. This trial provides evidence of improved effectiveness and safety for lifestyle intervention when combined with herbal medicines in women with PCOS. (6)

J Matern Fetal Neonat Med Jan 2018. Conclusions: Achillea millefolium (Yarrow) and Hypericum perforatum ointments reduce perineal pain level, redness, edema and ecchymosis of episiotomy wound, so it seems that consuming them was useful for episiotomy treatment. (7)

Wien Med Wochenshr Jun 2015. The results confirm the efficacy of the three herbal active substances (St. Johns Wort, Gingko, Lavender) in elderly patients of ≥ 60 years of age. In anxiety, depression, and dementia, they thus represent efficacious and well-tolerated alternatives to synthetic drugs. (8)

Psychiatr Pol Feb 2014. Results: 7 herbal remedies for which preclinical and clinical trials suggest their antidepressive influence have been identified: hypericum, lavender, borage, roseroot, chamomile, saffron and ginseng. For two of these, i.e. hypericum and saffron extracts, antidepressive effect in subjects with mild or moderate depression has been confirmed in controlled randomized clinical trials. (9)

Aging Ment Health 2014. Conclusion: St.Johns Wort and Eleuthero is superior to placebo in terms of overall treatment effectiveness and safety. Both response rate and remission rate among patients treated with the plants plus Antidepressants were significantly higher than those treated with Antidepressants alone. (10)

BMC Complement Altern Med. Jan 2014. Results: Acupuncture and herbal medicine (StJohns, Chaste, Gingko, Xiao yao san) treatments for premenstrual syndrome and premenstrual dysphoric disorder showed a 50% or better reduction of symptoms compared to the initial state. (11)

Int J Psychiatry Clin Pract Nov 2013. Results: In randomised, double-blind, controlled clinical trials the antidepressant effect of St Johns Wort was superior to that of the placebo and at least comparable to that of paroxetine (Paxil). The beneficial effect of St Johns is particularly pronounced with respect to the core symptoms of depression. (12)

J Cardiovasc Transl Res Jun 2013: Results: Residual platelet reactivity improved with St Johns during the first month post-cardiac surgery. (13)

Jundishapur J Nat Parm Prod 2012. Results: St Johns Wort, added to TriCyclic Antidepressants (TCAs) significantly improves depression over TCAs alone. It also eliminated the common side effects of sexual dysfunction and insomnia compared to TCAs alone. (14)

Australas J Dermatol May 2012. Results: Three factors, erythema, scaling and thickness, were evaluated; all were significantly lower where the formulated ointment had been applied. Hypericum perforatum ointment applied twice daily may be effective in reducing scores in mild plaque-type psoriasis. (15)

J Drugs Dermatol Feb 2012. Results: Use of the St Johns formulation was found to have no significant adverse effects and was well tolerated by participants. In patients with Herpes Simplex, statistically, odds for being affected by burning and stinging sensation were 1.9 times greater in the Acyclovir group in comparison to St Johns. Similarly, the odds of being affected by symptoms of acute pain, erythema and vesiculation were 1.8, 2.4, and 4.4 times higher in the Acyclovir group in comparison to the St Johns group. (16)

Got that? Gods medicine relieved the symptoms of Herpes 2-4X better than Mans medicine.

BMC Psychiatry Aug 2011. Conclusions: Analysis of the neurophysiological changes following the intake of St Johns, Passion Flower, and Valerian, balance revealed a similarity of frequency changes to those of calming and anti-depressive drugs on the EEG without impairment of cognition. (17)

Eur Neuropsychopharmacol Dec 2011. Results: Several of the plants provide a high level of evidence, such as Hypericum perforatum for major depression, and Kava for anxiety disorders. (18)

Phytomedicine Jun 2011. Results: In patients with Major Depression,Hypericum extract is more efficient in lowering the relapse and recurrence rates of responders, when compared to Celexa and placebo. In addition, duration of response was increased in the group treated with Hypericum extract. (19)

Menopause Mar 2010. Conclusions: St John’s wort can be used as an effective treatment for the vasomotor symptoms of perimenopausal or postmenopausal women. (20)

J Altern Complement Med Sep 2009. Conclusions: These results suggest a potentially significant clinical application for Chaste/St Johns in PMS-like symptoms among perimenopausal women. (21)

Menopause Ap 2009. Results: After 3 months of treatment, compared with the placebo group, women in the St. John’s wort group reported significantly better menopause-specific quality of life and significantly fewer sleep problems. (22)

Can Fam Physician. 2007 Sep. Results: Compared side by side to Paxil, a pharmaceutical prescribed for depression, and a placebo, St. Johns Wort decreased standardized depression questionnaire scores by 70% more than Paxil. And while both improved depression better than a placebo, St. John’s Wort showed results in a higher percentage of patients than Paxil (87 vs 60%) and remission (complete resolution) rates were higher. (71 vs 42%). (23)

J Clin Psychopharmacol Oct 2005. Conclusion: St John’s wort was significantly more effective than fluoxetine (Prozac). (24)

True Health shares St Johns Wort in True Mood Lift, True Viral Defense, and True Focus!

Eleuthero – Siberian Ginseng

August 19, 2020/0 Comments/in Home Remedies /by Dr. Todd Stone

Eleuthero: Scientific Evidence

Consider with Immune deficiency, convalescence, inflammatory conditions (-itis), Adrenal Fatigue, Asthma, Candida, Hypoglycemia, jet lag, hypothyroidism, and menopause. Use for fatigue, exhaustion, feeling stressed, and brain fog. Attributes – Adaptogen, Immune Regulating. Organ/Systems – Adrenal, Endocrine, Immune system. Cautions – High blood pressure

Randomized Clinical Trials (RCTs) are considered the highest form of scientific evidence. A group of people with the same condition are divided into two groups, and randomly assigned to receive the medicine or a placebo. Neither the patient nor the doctors know which group they are in until the results are assessed.

The following are RCTs in the National Library of Medicine listed when you search “Eleuthero double blind.”

Nutrients Jan 2020. Results: Eleuthero (and one other plant) significantly improved cognitive function, and reduced anxiety and uncertainty scores. (1)

J Int Soc Sports Nutr Nov 2015. Conclusions: The multi-ingredient product’s potential enhancement of Fatty Acid Oxidation during exercise, satiety, and Rate of Perceived Exertion reduction suggests an acute effectiveness of this medicine in improving the exercise-related fat loss benefits. (2)

Phytomedicine Dec 2015. Conclusion: A Traditional Chinese Medicine with Eleuthero exerted significant antitussive (cough relief) effects in Upper Respiratory Infections (URIs). (3)

Pharmazie Ap 2015. Results: Therefore, Eleuthero may have potential to reduce the severity of the alcohol hangover by inhibiting the alcohol-induced hypoglycemia and inflammatory response. (4)

J Int Med Res. Feb 2015. Conclusions: Eleuthero significantly improved the symptoms of burnout after 12 weeks’ use. (5)

Chin J Physiol Ap 2010. Results: This is the first well-conducted study that shows that 8-week Eleuthero supplementation enhances endurance capacity, elevates cardiovascular functions and alters the metabolism for sparing glycogen in recreationally trained males. (5)

Phytomedicine Jun 2010. Results: The subjects in the Eleuthero group quickly gained improved attention and increased speed and accuracy during stressful cognitive tasks, in comparison to placebo. There was also a tendency of the medicine to reduce percentage of errors, which means better accuracy, quality of the work, and degree of care in the volunteers under stressful conditions. (6)

Korean J Physiol Pharmacol Feb 2009. Results: In this population of patients with knee osteoarthritis, Eleuthero (with 2 other plants) was found to be safe, tolerable and effective for symptomatic improvement of pain and physical function. (7)

Phytomedicine Nov 2005. Results: Both the clinical and laboratory results of the present study suggest that Eleuthero, Rhodiola, and Schizandra can be recommended in the standard treatment of patients with acute non-specific pneumonia as an adjuvant to increase the Quality Of Life and to expedite the recovery of patients. (8)

Phytomedicine Aug 2005. Results: The significance of the results obtained in this study is discussed with respect to the efficacy of KanJang (Eleuthero, Echinacea, Adhatoda) for the treatment of acute respiratory infection and to the concept that multi-plant therapy offers higher efficacy compared with mono-plant treatment of such infections. (9)

Like True Cold/Flu Relief! Several supportive plants to heal fast!

Phytomedicine May 2003: It works for Familial Mediterranean Fever too! (10)

Phytomedicine Oct. 2002: It worked for Upper Respiratory Infections including sinus infection. (11)

Arzneimittelforschung Oct 1987. Results: The most salient feature in the Eleuthero group was a drastic increase in the absolute number of immunocompetent cells, with an especially pronounced effect on T lymphocytes, predominantly of the helper/inducer type, but also on cytotoxic and natural killer cells. In addition, a general enhancement of the activation state of T lymphocytes was observed. No side effects were observed during the trial or afterwards (observation period 6 months). (12)

Nutr Res Jul 2016. Results: Thus, we demonstrate that Siberian ginseng exerts its potent anti-edema activity mainly by promoting lymphatic function. (13)

Cochran Database Syst Rev Jul 2009. Results: Eleuthero was associated with a significant increase in the number of participants whose neurological impairment improved after acute ischemic stroke. (15)

J Bone Miner Metab 2009. Results: This study suggests that Eleuthero supplementation may have beneficial effects on bone remodeling in postmenopausal women and that it has no significant adverse events. (16)

Biochem Biophys Res Commun. Oct 2008. Results: These results suggest that Eleuthero supplementation may have beneficial effects against oxidative stress (anti-aging!) and improve serum lipid profiles without subsequent side effects. (17)

Zhongguo Zhong Yoa Za Zhi Ap 2005. Conclusion: Eleuthero can regulate the cellular immunity and factor, indicating that it can be used as an assistant drug to regulate the function of cellular immunity in the patients with lung cancer. (18)

Phytotherapy Res. Feb 2000. Results: On the basis of the present study the following conclusions were drawn: active components in Eleuthero affect cellular defence and physical fitness, as well as lipid metabolism. (19)

True Health offers Eleuthero in True Energy Boost, Calm Masculine Strength and Calm Feminine Vitality!

Echinacea – Coneflower

August 19, 2020/0 Comments/in Home Remedies /by Dr. Todd Stone

Echinacea: Scientific Evidence

Allergy Randomized Clinical Trials (RCTs) are considered the highest form of scientific evidence. A group of people with the same condition are divided into two groups, and randomly assigned to receive the medicine or a placebo. Neither the patient nor the doctors know which group they are in until the results are assessed.

The following are RCTs in the National Library of Medicine listed when you search “Echinacea double blind.”

Phytotherapy Res Mar 2020. Results: These findings suggest that particular Echinacea preparations have significant beneficial effects on anxiety in humans. (1)

J Dermatol Sci Oct 2017. Conclusion: The investigated Echinacea extract shows great potential in alleviating cutaneous symptoms of Atopic Eczema, and by exerting remarkable anti-inflammatory actions and restoring the epidermal lipid barrier, it will be very likely a well-tolerated, powerful novel ingredient for the adjuvant therapy of Atopic Eczema. (2)

Phytomedicine Dec 2015. Conclusion: A Traditional Chinese Medicine with Echinacea exerted significant antitussive (cough relief) effects in Upper Respiratory Infections (URIs). (3)

Curr Ther Res Clin Exp Ap 2015. Results: Echinacea was slightly better than Tamiflu at relieving the symptoms of Influenza. (4)

Elderberry worked 4 times faster than Tamiflu, which is in our Cold/Flu Medicine, along with Echinacea and a few others.

Wien Med Wochenschr Feb 2013. Results: Echinacea is efficacious and safe in respiratory tract infections for long-term and short-term prevention as well as for acute treatment. (5)

Evid Based Complement Alternat Med 2012. Results: Echinacea reduced the total number of cold episodes, cumulated episode days within the group, and pain-killer medicated episodes. Echinacea inhibited virally confirmed colds and especially prevented enveloped virus infections. Echinacea showed maximal effects on recurrent infections, and preventive effects increased with therapy compliance and adherence to the protocol. (6)

J Strength Cond Res Jul 2012. Results: These data suggest that Echincea supplementation results in significant increases in EPO (erythropoietin), VO2max, and running economy. (7)

Evid Based Complement Alternat Med 2012. Results: Supplementation with Echinacea, if taken before and during travel, may have preventive effects against the development of respiratory symptoms during travel involving long-haul flights. (8)

J Am Dent Assoc. Oct 2011. Conclusions: Topical treatment by means of the THPP (topical herbal periodontal patch) may be effective and safe in reducing topical gingival inflammation. (9)

Int J Gen Med Jan 2011. Results: The mean percentage reduction in total symptom severity scores from baseline at days 4 and 8 was significantly greater in the Echinacea/Zinc/Vit.C group than in the placebo group, for the common cold. (10)

J Clin Pharm Ther Oct 2011. Results: Echinacea, Zinc, Vitamin C significantly reduced exacerbations of COPD during upper respiratory infections in patients with COPD. (11)

Eur J Med Res Sep 2009. Conclusion: An echinacea/sage preparation is as efficacious and well tolerated as a chlorhexidine/lidocaine spray in the treatment of acute sore throats. (12)

J Altern Complement Med Dec 2005. Results: Use of Echinacea was associated with a 28% decreased risk of subsequent Upper Respiratory Infections, in children. (13)

Phytomedicine Nov 2005. Results: This study demonstrates the efficacy and safety of Echinacea, Wild Indigo, and Thuja in the treatment of URIs, and that its efficacy is dose dependent. (14)

Arch Pediatr Adolesc Med Mar 2004. Conclusion: A preventive effect of a product containing echinacea, propolis, and vitamin C on the incidence of respiratory tract infections was observed. (15)

J Clin Pharm Ther Feb 2004. Conclusions: Early intervention with a standardized formulation of echinacea resulted in reduced symptom severity in subjects with naturally acquired upper respiratory tract infection. (16)

True Health features Echinacea in True Allergy Relief, True Cold/Flu Relief, True Lymph Cleanse, True GI Cleanse, and True Viral Defense.

DrStone

Milk Thistle – Silybum Marianum

August 17, 2020/0 Comments/in Home Remedies /by Dr. Todd Stone

Milk Thistle: Scientific Evidence

The following are RCTs in the National Library of Medicine listed when you search “Silymarin double blind.”

Phytotherapy Res. Aug 2020. The results showed that S. marianum can decrease frequency and severity of hot flashes significantly in Menopause. (1)

Phytotherapy Res. Feb 2019. Results: Prophylactic administration of silymarin gel could significantly reduce the severity of radiodermatitis and delay its occurrence after 5 weeks of application. (2)

Radiodermatitis is being burned by radiation from your doctors care.

J Evid Based Complementary Altern Med Oct 2017. Results: The mean serum fasting blood glucose, glycosylated hemoglobin (overall blood sugar control), and triglyceride in the herbal drug group were significantly less than placebo group’s values after 3 months of the intervention, in Diabetic patients. The “drug” was Milk Thistle, Stinging Nettle, and Frankincense. (3)

J Biol Regul Homeost Agents Jun 2017. Results: 136 obese subjects with T2DM (Diabetes) and metabolic syndrome were analyzed for fasting blood glucose and insulin, Insulin Resistance, total, HDL and LDL cholesterol, triglycerides, uric acid, BMI, waist circumference, waist to hip ratio and underwent bioelectrical impedance to assess % of abdominal fat. All the above-mentioned parameters, as recorded at enrollment, after 6 months and at the end of the study, had significantly improved in the Milk Thistle / Barberry-treated group in respect to baseline and to the control group. A validated national cardiovascular risk score also improved significantly after treatment in respect to placebo. Our results point to a clinically significant effect in obese people with T2DM and metabolic syndrome. Moreover, for the first time, they provide evidence of a significant uric acid lowering activity as an additive beneficial effect of Milk Thistle / Barberry. (4)

True HM Detox is our product with Milk Thistle and Barberry.

Phytotherapy Res. Nov 2016. Results: Prophylactic administration of silymarin tablets significantly reduced the severity of radiotherapy induced mucositis and delay its occurrence in patients with head and neck cancer. (5). Proven to reduce the severity of the harm caused by your doctor.

Clin Nutr. Oct 2016. Conclusions: The addition of B. aristata/S. marianum to insulin therapy in patients with type 1 diabetes mellitus leads to a reduction of the insulin dose necessary to have an adequate glycemic control. (6)

Phytomedicine Feb 2015. Results: fasting plasma glucose, insulin, and HOMA-index levels (Insulin Resistance) were reduced by Milk Thistle / Barberry, but not by placebo. (7)

J Biol Regul Homeost Agents Jun 2014. Results: a combination of red yeast rice, Silybum marianum and octasonol was effective in improving lipid profile, endothelial, and inflammatory parameters in dislipidemic patients. (8)

Phytomedicine Dec 2013. Results: Use of selenium-silymarin mix reduces lower urinary tract symptoms and prostate specific antigen in men. (9)

Eur J Haematol Mar 2013. Results: Serum ferritin levels decreased significantly from the beginning to the end of silymarin treatment in patients with Thalassemia. (10)

Biomed Pap Med Fac Univ Palacky Olomouc Czech Republic. Sep 2010. Results: This suggests that Milk Thistle and Selenium may be effective in reducing Prostate Cancer progression. (11)

Prog Neuropsychopharmacol Biol Psychiatry Mar 2010. Results: Milk Thistle worked just as well as Prozac in the treatment of OCD. (12)

Cancer Jan 2010. Conclusions: In children with acute lymphoblastic leukemia (ALL) and liver toxicity, Milk Thistle (MT) was associated with a trend toward significant reductions in liver toxicity. MT did not antagonize the effects of chemotherapy agents used for the treatment of ALL. (13)

Again, Plant Medicine protecting patients from the damage of Modern Medicine.

J Clin Pharmacol Ap 2010. Results: Silymarin has been shown to decrease the complications of liver disease and mortality in patients with cirrhotic disease, and is safe at higher than normal doses. (14)

Transpl Int. Jul 2014. Results: Milk Thistle has a significant antiviral activity in patients with established HCV (Hepatitis C). (15)

BMC Dermatol Oct 2012. Conclusions: Silymarin showed tremendous improvement of melasma (brown spots on skin) in a dose-dependent manner, and was effective in prevention of skin damage caused by U.V. sunlight. (16)

Chin J Integr Med Dec 2015. Results: Disease Activity Index significantly decreased in the silymarin group in patients with Ulcerative Colitis. (17)

Free Radic Biol Med May 2012. Results: In patients with Fatty Liver, Treatment with Silymarin and PhosphatidylCholine but not Placebo for 12 months was associated with improvement in liver enzymes, insulin resistance, and liver histology (tissue health). (18)

Otolaryngol Head Neck Surg. Dec 2011. Conclusion: Considering the statistically effective role of silymarin in alleviating the severity of allergic rhinitis symptoms, applying this herbal antioxidant along with other medications may result in better management. (19)

Phytomedicine May 2009. Results: No adverse events were noted and both silymarin and placebo were well tolerated. Patients randomized to the silymarin group had quicker resolution of symptoms related to Acute Hepatitis. Biliary retention: dark urine, jaundice and scleral icterus. (yellow eyes). (20)

J Cosmet Dermatol. Mar 2008. Conclusions: The combination of silymarin and MSM can be useful in managing symptoms and condition of rosacea skin, especially in the rosacea subtype 1 erythemato-telangiectatic phase. (21)

Phytother Res Dec 2006. Results: The results showed a significant decrease in HbA1c (overall blood sugar regulation), Fasting Blood Sugar, total cholesterol, LDL, triglyceride SGOT and SGPT levels (Liver function) in silymarin treated patients compared with placebo as well as with values at the beginning of the study in each group. In conclusion, silymarin treatment in type II diabetic patients for 4 months has a beneficial effect on improving the glycemic profile. (22)

True Health offers True HM Detox, featuring Milk Thistle, in our online store!

-DrStone